Defective Esterase and Kinin-Forming Activity in Human Fletcher Trait Plasma
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چکیده
منابع مشابه
Defective Esterase and Kinin-Forming Activity in Human Fletcher Trait Plasma
Fletcher trait plasma failed to generate kinin and developed only a small amount of arginine esterase activity at an abnormally slow rate following surface activation. Neither defect was due to a deficiency of Hageman factor (HF, factor XII) or kininogen or to an excessively rapid inactivation of evolving kinin. Pyrex pretreated with Fletcher trait plasma did not generate kinin normally in fres...
متن کاملDefective Esterase and Kinin-Forming Activity in Human Fletcher Trait Plasma A FRACTION RICH IN KALLIKREINLIKE ACTIVITY By Virginia
Fletcher trait plasma failed to generate kinin and developed only a small amount of arginine esterase activity at an abnormally slow rate following surface activation. Neither defect was due to a deficiency of Hageman factor (HF, factor XII) or kininogen or to an excessively rapid inactivation of evolving kinin. Pyrex pretreated with Fletcher trait plasma did not generate kinin normally in fres...
متن کاملDefective esterase and kinin-forming activity in human Fletcher trait plasma. A fraction rich in kallikreinlike activity.
Fletcher trait plasma failed to generate kinin and developed only a small amount of arginine esterase activity at an abnormally slow rate following surface activation. Neither defect was due to a deficiency of Hageman factor (HF, factor XII) or kininogen or to an excessively rapid inactivation of evolving kinin. Pyrex pretreated with Fletcher trait plasma did not generate kinin normally in fres...
متن کاملDefective activation of clotting, fibrinolytic, and permeability-enhancing systems in human Fletcher trait plasma.
When normal plasma is exposed to foreign surfaces, Hageman factor (HF, factor XII) is activated; under appropriate circumstances, it then initiates reactions leading to coagulation, fibrinolysis, increased vascular permeability, esterolytic activity, and kinin formation. However, coagulation, fibrinolysis, and increased vascular permeability were impaired in plasma from an individual with Fletc...
متن کاملStudies on Fletcher trait and Fitzgerald trait
The way by which contact of blood with foreign surface accelerates clotting has been elucidated from the discovery of four rare disorders of blood coagulation; Hageman trait, plasma thromboplastin antecedent (PTA) deficiency, Fletcher trait, and Fitzgerald trait. Interestingly, it was unexpectedly found that Fletcher factor is plasma prekallikrein and Fitzgerald factor is high-molecular-weight ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1974
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.34.5.652